parathyroid adenoma localization
نویسندگان
چکیده
background: bilateral neck exploration is the gold standard for parathyroid adenoma localization in primary hyperparathyroidism. but surgeons do not have adequate experience for accurate surgical exploration and new methods are developed for surgery like unilateral exploration and minimally invasive surgery, thus, preoperative localization could reduces time and stress in surgical performance. method: 80 patients with documented primary hyperparathyroidism and with raised serum calcium and parathyroid hormone (pth) were selected. the results of ultrasonographic localization for each patient were compared with findings of surgery and 99m technetium sestamibi scintigraphy. also variables such as preoperative serum calcium, pth level and adenoma weight were compared between patients who had localized and nonlocalized adenoma with ultrasonography or sestamibi scan. the data was compared with student’s t-test. results: in a prospective diagnostic tests’ accuracy, 80 patients with primary hyperparathyroidism were enrolled. ultrasonography images detected enlarged parathyroid glands in 61 of 80 patients (76.3%) with sensitivity of 83.5% and positive predictive value (ppv) of 89.7%. sestamibi scintigraphy detected adenoma in 63 patients (78.8%) with sensitivity of 85% and ppv of 91.3%. there was no significant deference between ultrasonography and scintigraphy in localization of adenomas. both ultrasonography and scintigraphy used for determining localization, and they located 73 adenomas (91.3%) with sensitivity of 97.3% and ppv of 93.5%. conclusion: ultrasonography as an accurate method for localization of enlarged parathyroid glands in primary hyperparathyroidism, is comparable in overall utility with sestamibi scintigraphy. this study suggests a strategy for initial testing with one method, followed by the alternate imaging test if the first test happen to be negative.
منابع مشابه
Parathyroid adenoma Localization
Background: Bilateral neck exploration is the gold standard for parathyroid adenoma localization in primary hyperparathyroidism. But surgeons do not have adequate experience for accurate surgical exploration and new methods are developed for surgery like unilateral exploration and minimally invasive surgery, thus, preoperative localization could reduces time and stress in surgical performance....
متن کاملParathyroid adenoma Localization
BACKGROUND Bilateral neck exploration is the gold standard for parathyroid adenoma localization in primary hyperparathyroidism. But surgeons do not have adequate experience for accurate surgical exploration and new methods are developed for surgery like unilateral exploration and minimally invasive surgery, thus, preoperative localization could reduces time and stress in surgical performance. ...
متن کاملLocalization of ectopic parathyroid adenoma with Tc-99m-MIBI [Persian]
Ectopic paratliyroid adenoma might create a clinical dilemma in patients with hypercalcemia. Radioisotopic scan is a sensitive and noninvasive method which can be useful in these patients. In this report a case of ectopic parathyroid adenoma is presented and the usefulness of TC-99m-MIBI scintigraphy as compared with other modalities is discussed.
متن کاملlocalization of ectopic parathyroid adenoma with tc-99m-mibi [persian]
ectopic paratliyroid adenoma might create a clinical dilemma in patients with hypercalcemia. radioisotopic scan is a sensitive and noninvasive method which can be useful in these patients. in this report a case of ectopic parathyroid adenoma is presented and the usefulness of tc-99m-mibi scintigraphy as compared with other modalities is discussed.
متن کاملSensitivity and specificity of thallium-technetium subtraction scan in localization of the parathyroid adenoma [Persian]
Thirty one patients with biologic and clinical diagnosis of hyperparathyroidism were submitted to thalium-technetium scan prior to exploration of the neck. Scan findings were compared with the pathologic results. Surgical exploration of the neck showed a parathyroid adenoma in 24 patients, parathyroid carcinoma in one patient, normal parathyroid in another patient and parathyroid hyperplasia in...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
medical journal of islamic republic of iranجلد ۲۶، شماره ۳، صفحات ۱۰۳-۱۰۹
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023